2021 Feb 2x Guyon N et al are out!
Network asynchrony underlying increased broadband gamma power
Nicolas Guyon, Leonardo Rakauskas Zacharias, Eliezyer Fermino de Oliveira, Hoseok Kim, João Pereira Leite, Cleiton Lopes-Aguiar and Marie Carlén
Journal of Neuroscience 2021 Mar 31;41(13):2944-2963. LINK
Adult trkB signaling in pavalbumin interneurons is essential to prefrontal network dynamics
Nicolas Guyon, Leonardo Rakauskas Zacharias, Josina Anna van Lunteren, Jana Immenschuh, Janos Fuzik, Antje Märtin, Yang Xuan, Misha Zilberter, Hoseok Kim, Konstantinos Meletis, Cleiton Lopes-Aguiar and Marie Carlén
Journal of Neuroscience 2021 Apr 7;41(14):3120-3141. LINK
2021 Feb BOOK CHAPTER: Neuronal oscillations and the mouse prefrontal cortex

Felix Jung, PhD student in the lab, and Marie Carlén review findings on the role of neuronal oscillations in prefrontal functioning, with a specific focus on research in mice. We discuss discoveries pertaining to local prefrontal processing, as well to interactions with other brain regions. We also discuss how the recent discovery of brain-wide respiration-entrained rhythms (RR) warrant re-evaluation of certain findings on slow oscillations (<10 Hz) in prefrontal functioning.

Neuronal oscillations and the mouse prefrontal cortex.
Jung F, Carlén M.
(2021) International Review of Neurobiology.
ISSN 0074-7742. Elsevier Inc. https://doi.org/10.1016/bs.irn.2020.11.005

2021 Feb Katharina Heining joins the CarlenLab

Feb 1 2021

Katharina Heining joins the CarlénLab as postdoctoral researcher!

Katharina will work on the project “A functional map of the mouse prefrontal cortex” and is funded by a postdoctoral fellowship from the Wenner-Gren Foundations. Link to the foundation HERE

Welcome Katharina!

2020 Sep CarlenLab receives 32.2M SEK grant

Sep 30 2020

The CarlénLab receives 3.0M€ (32.2M SEK) for the project “Brain circuits in decision-making” from the Knut & Alice Wallenbergs Foundation!

The project will run over 5 years and be conducted in collaboration with the lab of KONSTANTINOS MELETIS.   The interactions between the prefrontal cortex and the striatum will be studied with large-scale electrophysiology and calcium imaging in behaving mice.

Link to funded KAW projects 2020 here

2020 Sep Sofie Ährlund-Richter receives the Brain Diseases Award 2020

CarlenLab alumni Sofie Ährlund-Richter receives the Brain Diseases Award 2020 from the UZH Foundation for her PhD thesis work ‘On the neuronal correlates of cognition; cell-type specific circuitry and function of the prefrontal cortex!

Congratulations Sofie! 

2020 Aug Marina Slashcheva selected for the MSCA ITN position

August 2020

UPDATE: Marina Slashcheva has been selected for the PhD position in the CarlenLab within the Marie Sklodowska-Curie Action MSC-ITN-2019 project euSNN, European School of Network Neuroscience, www.eusnn.eu

The CarlenLab received 68 applications from 23 different countries.

Welcome Marina!

2020 July The DMCdrive goes live!

July  2020

The DMCdrive goes live!

Want to long-term record and manipulate neuronal activity in freely moving mice or rats? Then we strongly recommend going for our DMCdrive holding four movable tetrodes + optical fiber, that can be built from 3D printed parts in 4h without much experience. Very reliable optotagging and recovery of single unit and LFP activities over many days.
Designed by senior researcher Hoseok Kim.

Open access to the publication here.

May 2020 Postdoc Pierre Le Merre receives StratNeuro funding for postdoctoral work

May 2020

CarlenLab postdoc Pierre Le Merre receives StratNeuro funding for postdoctoral researchers 2020!

StratNeuro, the Strategic Research Area Neuroscience joins Karolinska Institutet, The Royal Institutet of Technology (KTH) and Umeå University and has the mission to integrate clinical and basic research to foster a new generation of leaders and scientists in translational neuroscience. Read more here.

Congratulations Pierre!

2019 Sep Postdoc Pirre Le Merre receives 2019 NARSAD YIA

September 2019

CarlenLab postdoc Pierre Le Merre receives 2019 NARSAD Young Investigator Grant!

The NARSAD Young Investigator Grants were initiated to fund innovative, cutting-edge research projects relevant to serious brain and behaviour disorders such as schizophrenia, mood disorders, anxiety disorders or child and adolescent mental illnesses.

Pierre Le Merre, from the Department of Neuroscience at Karolinska Institutet, is one of the “promising young candidates with innovative ideas within the field of mental health research” to receive the two-year grant.

The grant, which offers 35 000 USD per year for two years, will enable him to identify the neuronal determinants of working memory in the prefrontal cortex. Working memory is a core cognitive function affected in mental disorders such as schizophrenia. Therefore, this research programme aims to diagnose better and treat the cognitive deficits of schizophrenia.”

Link: KI announcement

Link: Brain & Behavior Research Foundation Grants

Link: The Brain and Behavior Research Foundation

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